The hosts, who occupy eighth position in the Turkish Super Lig table, will be aiming to end a six-game winless run.
Kayserispor head into the penultimate game of the season off the back of a poor run of form, picking up just two points in six matches.
In their last two outings, Kayserispor have lost to Alanyaspor and Fatih Karagumruk, failing to score in both of those contests.
Although they have drawn a blank in consecutive matches, Cagdas Atan may have greater concerns about his side's recent defensive performances.
They have shipped 19 goals across their previous six matches, conceding at least four times in three of those contests.
Saturday's hosts have tended to offer stronger defensive performances at home, though, having kept seven of their nine clean sheets this season at the Kadir Has Stadium.
After their Turkish Cup final dreams were ended in the semi-finals by Istanbul Basaksehir, Ankaragucu returned to league action with a home fixture against Galatasaray.
Ankaragucu were unable to mount a fightback in the second period, conceding two more goals as they fell to a 4-1 defeat that clinched Galatasaray the title and left Tolunay Kafkas' side in 13th position.
With two five points separating them from the relegation zone, Ankaragucu are well placed to secure survival, and they will want to guarantee their safety this weekend.
After winning 2-1 in the reverse fixture with Kayserispor, Ankaragucu will have the chance to complete a league double on Saturday.
As for the visitors, they are still unable to call upon Uros Radakovic, who remains in the treatment room with a knee injury.
After finding the net in each of his last three league appearances, Milson is expected to retain his place in the side.
Kayserispor possible starting lineup:
Akkan; Malcuit, Kizildag, Mujakic; Kitsiou, Dokanovic, Antalyali, Hanousek; Kilinc, Milson, Sowe
Ankaragucu possible starting lineup:
Bayazit; Sazdagi, Attamah, Kolovetsios, Kocaman; Uzodimma, Karimi; Kemen, Mensah, Mane; Thiam
We say: Kayserispor 1-2 Ankaragucu
Ankaragucu have won two of their last three away league matches, and we think that they will take advantage of a vulnerable Kayserispor defence to claim another victory on Saturday.
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