Zdenek Zeman has opted for a three-man attack of Francesco Totti, Mattia Destro and Eric Lamela for today's visit of Bologna.
Totti managed to overcome an injury to take his place in the starting lineup, while the Giallorossi also welcome back Federico Balzaretti from a thigh problem.
Daniele De Rossi and Michael Bradley both miss out through injury, while Daniel Osvaldo is suspended.
Alberto Gilardino starts up front for the visitors, supported by Alessandro Diamanti and Panagiotis Kone.
Roma: Stekelenburg; Piris, Burdisso, Castan, Balzaretti; Florenzi, Tachtsidis, Pjanic; Lamela, Destro, Totti
Bologna: Agliardi; Motta, Antonsson, Cherubin, Morleo; Taider, Perez, Guarente; Kone, Diamanti; Gilardino