The Bluebirds and the Rams both played out 1-1 draws in their last fixtures to continue their positive runs of form.
Cardiff's six-match winning streak may have come to an end against Middlesbrough on Saturday, but a point at the Riverside can be considered a positive result.
Having climbed into the top six with victory over Bournemouth earlier in the week, Cardiff dropped below the Cherries and surprise package Barnsley with the draw.
However, Mick McCarthy's men are only two points off Bournemouth and a further two points behind fifth-placed Reading, the latter of whom they still have to face.
Cardiff remain unbeaten since McCarthy took over from Neil Harris in January, winning six and drawing three, compared to five league losses on the spin before he was appointed.
Derby have also turned their season around of late under rookie boss Wayne Rooney, moving up to 18th and nine points above the relegation zone with a run of two losses in nine.
The Rams have won six of those matches, though they had to settle for a point against East Midlands rivals Nottingham Forest last time out.
Rooney's charges have taken 18 points on their travels this term, which is a similar record to Cardiff at home, the Bluebirds having taken 21 points from a game more.
However, Derby have won just one of their last six meetings with City in the Championship, most recently playing out a 1-1 draw in the reverse fixture four months ago.
Cardiff City Championship form: WWWWWD
Derby County Championship form: LWWLWD
McCarthy named an unchanged starting lineup for the trip to Middlesbrough, but the experienced coach may be tempted to change things around during this gruelling run of games.
Striker Kieffer Moore did not find the net last time out, but he has 15 goals in 29 league games this season and is a certain starter up top.
As for the visitors, they are sweating on the fitness of goalkeeper David Marshall, one of the heroes of Cardiff's promotion campaign in 2012-13.
The Scotland international injured his back against Forest and will be assessed, but it looks like Kelle Roos may have to step in.
Cardiff City possible starting lineup:
Phillips; Morrison, Flint, Nelson; Ng, Vaulks, Ralls, Bennett; Ojo, Moore, Wilson
Derby County possible starting lineup:
Roos; Byrne, Wisdom, Clarke, Buchanan; Bird, Shinnie; Waghorn, Knight, Jozwiak; Kazim-Richards
We say: Cardiff City 2-1 Derby County
Cardiff will be eager to get back to winning ways on Tuesday in order to climb back into the top six, while Derby could do with putting some further distance between themselves and the bottom three.
The Bluebirds have won back-to-back league matches on home soil and we are backing them to make it three in a row in South Wales for the first time since March 2018 with three points here.