Luton have won each of their last 16 FA Cup ties as a Football League club against teams from a lower division, and they will be regarded as favourites to come out on top on Saturday.
Grimsby, meanwhile, have struggled away from home in recent weeks, losing five of their last six matches on the road, and another defeat could be on the cards at Kenilworth Road.
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Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Luton Town win with a probability of 52.63%. A win for Grimsby Town had a probability of 24.25% and a draw had a probability of 23.1%.
The most likely scoreline for a Luton Town win was 2-1 with a probability of 9.75%. The next most likely scorelines for that outcome were 1-0 (9.39%) and 2-0 (8.47%). The likeliest Grimsby Town win was 1-2 (6.23%), while for a drawn scoreline it was 1-1 (10.81%). The actual scoreline of 2-2 was predicted with a 5.6% likelihood.