Such a stronghold last term, Napoli have already lost eight games this season at the Maradona in all competitions - five of them in the league - so are certainly vulnerable to an adventurous away side with nothing to lose.
Sassuolo can push their hosts all the way with an attacking lineup the envy of much bigger clubs, but Spalletti's men are not finished yet and can at least take a point in their pursuit of taking third place ahead of Juventus.
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Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Napoli win with a probability of 57.08%. A win for Sassuolo had a probability of 22.71% and a draw had a probability of 20.2%.
The most likely scoreline for a Napoli win was 2-1 with a probability of 9.4%. The next most likely scorelines for that outcome were 2-0 (7.01%) and 3-1 (6.91%). The likeliest Sassuolo win was 1-2 (5.71%), while for a drawn scoreline it was 1-1 (8.52%). The actual scoreline of 6-1 was predicted with a 0.6% likelihood. Our data analysis correctly predicted that Napoli would win this match.