Recent masters of winning without conceding, Roma will fancy their chances of cancelling out their deficit at a sold-out Stadio Olimpico, but overall victory could ultimately prove beyond them.
With a talented squad and a winning mentality, it could instead be Feyenoord who will face either Bayer Leverkusen or Union Saint-Gilloise in next month's semi-finals.
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Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Feyenoord win with a probability of 39.77%. A win for Roma had a probability of 34.15% and a draw had a probability of 26.1%.
The most likely scoreline for a Feyenoord win was 0-1 with a probability of 9.83%. The next most likely scorelines for that outcome were 1-2 (8.57%) and 0-2 (6.79%). The likeliest Roma win was 1-0 (8.97%), while for a drawn scoreline it was 1-1 (12.39%).